Feedback and Suggestions from Stuart
S5 Propelling motion: Stronger propelling motion. Small molecules not consistent with rest of the animations -> maybe use medium sized spheres (transparent) to indicate presence of molecules without showing what they are. When ligand moves forward, grey spheres get pushed out. Helper Molecule: Hooking motion might not work -> reduces the radius of ligand movement mechanism too much? Use a bigger helper molecule S3. Specific: 3 red arrows, 1 blue arrow Any: all four arrows sta
nParticles, and xGen expressions
nParticle Creation Expression: to make instanced objects different radius -> for collision purposes One for CustomIndex -> for instancing differe molecules one for radiusPP. -> first must break connection at RadiusPP's original expression. float $random = rand(0,3); CustomIndex = $random; if ($random < 1 ) { radiusPP = .25; } else if ($random >= 1 && $random < 2 ) { radiusPP = 5; } else { radiusPP = 1.5; } Under offset: to bob spheres up and down $a = ((50 - $frame) / 24); .5
REB edits
REB revisions. Questions raised prior to sending forms in (aiming for Monday) Q26.b: Research risk: estimated to be low. Should it be medium? Risk so far justified to be low due to the lack of consequences. However, one could argue it to be medium due to testing anxiety.


S5 Q1 + Q4 Playblasts
Version 2: Better ligand movement towards receptor Version 3 : More turbulance for the small molecules. Smoother ligand movement Random version! S5Q4

S5Q1
In this shot, the ligand is pushing itself through the EC environment towards the receptor. What is the mechanism of an extracellular molecule’s movement towards a receptor The extracellular molecule propels itself. In the final version, the ligand would also be randomly rotating before it "propels" itself into the right position to situate in the receptor. nParticles are in place of actualy molecules in the environment in this playblast. In the final, the environment should

S10 Q1 full render!
Still has problems with particles going through each other. Simplest solution is increasing npartical self-colliding radius however: because molecules are in vast different sizes, and we want to show the environment to be crowded -> how to make some nparticles bigger than others? Possible solution via expression? Self-Collide radius vary via Custom Index #? I have yet to find the code for it..... Other potential solutions -> render in different layers? Use bullet system for t

Gifs! S2Q3
It's a gif! B. Based on your previous answer and assuming there are several instances of the complementary receptor present, an extracellular molecule tries to move toward: Whichever instance of the complementary receptor is closest Comments and feedback on potential changes: Somehow draw more attention to the ligand at the beginning Ligand: move that towards the center so it catches attention better. Add shakey motion to imply random motion of the ligand, although overall m

S4 Update
General Setup: Membrane and nucleus present in every answer, so the membrane and nucleus will be rendered separate from the ligand. It can sense the receptor from a distance: Ligand will move It has hard-wired knowledge: Ligand travels along a path towards receptor. Path will be drawn in aftereffects It receives a message from else where : Signal comes from nucleus -> particle emitters It can sense the receptor when it is close to it : wobbly signaling from receptor. Problems

S4 Setup
Not much going on here yet, just setting up plasma mb with nucleus and ligand. It might look something like this after composition:

S10 Q1 Re-make
For the question: J.Inside a cell, large molecules are densely crowded so much so that the average distance between two macromolecules is typically less than the width of a single macromolecule Changes made: Scene is relit so that overall the scene is bright Different material + colors added to molecules within the scene -> individual macromolecules can be differentiated from each other Removal of small molecules -> scene will no longer have arbituary water molecules (reasons